STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_2820DUF1707 domain-containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (230 aa)    
Predicted Functional Partners:
SPRI_5332
Phage-shock protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.821
SPRI_3099
Histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
    0.781
whiB-4
WhiB family transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
       0.742
SPRI_5333
F0F1 ATP synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.727
SPRI_2331
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.635
SPRI_5118
Lipoprotein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.589
SPRI_2823
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
       0.555
fumC
Aspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
       0.555
SPRI_2828
DUF402 domain-containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.555
SPRI_4941
Peptidase M48; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.535
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.