Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_2828DUF402 domain-containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (242 aa)    
Predicted Functional Partners:
fumC
Aspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
       0.781
SPRI_2826
Ricin B lectin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.707
SPRI_2820
DUF1707 domain-containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.530
SPRI_2823
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
       0.530
SPRI_3956
Methyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.530
whiB-4
WhiB family transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
       0.525
SPRI_6345
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.498
SPRI_2829
Magnesium or manganese-dependent protein phosphatase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.454
SPRI_1616
Iron-sulfur protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.430
SPRI_5148
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.427
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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