Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SPRI_2931Cystathionine gamma-synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (384 aa)    
Predicted Functional Partners:
SPRI_4467
Cystathionine beta-synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.996
SPRI_6448
Cysteine synthase/cystathionine beta-synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.963
SPRI_0180
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.959
SPRI_5899
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.959
SPRI_3595
Bifunctional beta-cystathionase/maltose regulon regulatory protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.952
SPRI_1856
Homocysteine methyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.944
SPRI_1660
Nitrite/sulfate reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 
 0.936
SPRI_2341
Branched-chain amino acid aminotransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.920
SPRI_6019
Class IV aminotransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.920
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 0.919
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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