STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_2937DNA-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (140 aa)    
Predicted Functional Partners:
rbpA-2
Membrane protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
  
    0.670
SPRI_2042
dUTPase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.651
nucS
UPF0286 protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
  
     0.635
SPRI_3726
rRNA methyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.593
xseB
Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
  
    0.556
SPRI_6179
Transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.548
SPRI_6938
Methyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.532
SPRI_2675
Hydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.504
SPRI_3320
Fructose 2,6-bisphosphatase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.482
whiB-2
WhiB family transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.478
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.