STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_2947biotin--[acetyl-CoA-carboxylase] synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (285 aa)    
Predicted Functional Partners:
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 
 0.969
SPRI_4211
acetyl-CoA carboxylase subunit alpha; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.926
SPRI_3475
acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 
 0.924
SPRI_4765
Acetyl/propionyl CoA carboxylase alpha subunit; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.924
SPRI_0389
acyl-CoA carboxylase complex A subunit; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.919
SPRI_2955
acetyl-CoA carboxylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.919
SPRI_3474
Pyruvate carboxylase subunit A; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
  
 0.908
SPRI_1970
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
 
 
 0.889
SPRI_2948
methylmalonyl-CoA carboxyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.886
SPRI_2946
Adenylate cyclase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 0.830
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.