Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_2960Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (272 aa)    
Predicted Functional Partners:
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.956
SPRI_3427
Hypoxanthine phosphoribosyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
 0.948
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Adenosine deaminase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
 
 
 0.937
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Adenosine deaminase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
 
 
 0.937
SPRI_2962
Phosphomannomutase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.935
SPRI_3210
Adenine deaminase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.933
SPRI_6313
Ribonucleoside hydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.926
SPRI_0181
Ribokinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.922
SPRI_5341
Ribokinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.922
SPRI_1346
NAD-dependent deacetylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 0.914
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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