mdh protein (Streptomyces pristinaespiralis)

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mdh

Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)

Predicted Functional Partners:

SPRI_4216

0.998

SPRI_4812

0.998

SPRI_2823

0.997

fumC

0.993

SPRI_3067

0.985

SPRI_2612

0.967

SPRI_4590

0.967

SPRI_1970

0.957

SPRI_6612

0.956

pckG

0.948

Your Current Organism:

Streptomyces pristinaespiralis

NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SPRI_1970	SPRI_2612	SPRI_1970	SPRI_2612	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Malate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.956
SPRI_1970	SPRI_2823	SPRI_1970	SPRI_2823	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	0.681
SPRI_1970	SPRI_3067	SPRI_1970	SPRI_3067	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Isocitrate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.411
SPRI_1970	SPRI_4216	SPRI_1970	SPRI_4216	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Citrate synthase 2; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.	0.949
SPRI_1970	SPRI_4590	SPRI_1970	SPRI_4590	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Malate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.956
SPRI_1970	SPRI_4812	SPRI_1970	SPRI_4812	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Type II citrate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.	0.965
SPRI_1970	fumC	SPRI_1970	SPRI_2827	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Aspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.440
SPRI_1970	mdh	SPRI_1970	SPRI_3065	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.	0.957
SPRI_1970	pckG	SPRI_1970	SPRI_2904	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.	0.957
SPRI_2612	SPRI_1970	SPRI_2612	SPRI_1970	Malate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.956
SPRI_2612	SPRI_2823	SPRI_2612	SPRI_2823	Malate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	0.962
SPRI_2612	SPRI_3067	SPRI_2612	SPRI_3067	Malate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Isocitrate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.539
SPRI_2612	SPRI_4216	SPRI_2612	SPRI_4216	Malate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Citrate synthase 2; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.	0.896
SPRI_2612	SPRI_4590	SPRI_2612	SPRI_4590	Malate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Malate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.903
SPRI_2612	SPRI_4812	SPRI_2612	SPRI_4812	Malate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Type II citrate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.	0.896
SPRI_2612	fumC	SPRI_2612	SPRI_2827	Malate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Aspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.968
SPRI_2612	mdh	SPRI_2612	SPRI_3065	Malate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.	0.967
SPRI_2823	SPRI_1970	SPRI_2823	SPRI_1970	Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.681
SPRI_2823	SPRI_2612	SPRI_2823	SPRI_2612	Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	Malate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.962
SPRI_2823	SPRI_3067	SPRI_2823	SPRI_3067	Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.	Isocitrate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.978