STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_3067Isocitrate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (409 aa)    
Predicted Functional Partners:
SPRI_2599
Alpha-ketoglutarate decarboxylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.994
SPRI_1818
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 0.990
SPRI_2823
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.975
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 
 0.967
SPRI_5483
Glutamate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 0.963
SPRI_1893
Glutamate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.957
SPRI_3244
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.951
SPRI_6612
Isocitrate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family.
    
 0.926
SPRI_3245
2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.919
SPRI_4216
Citrate synthase 2; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.
  
 
 0.900
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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