Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
SPRI_3118Putative Two-component system response regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (203 aa)    
Predicted Functional Partners:
SPRI_2155
Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.867
SPRI_3117
RNA polymerase sigma factor SigD; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
  
    0.722
SPRI_5722
Diguanylate cyclase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.657
SPRI_2420
Histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   0.655
SPRI_6433
Histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   0.655
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.648
SPRI_5593
Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   0.621
SPRI_3115
Inosine-5-monophosphate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.618
SPRI_5334
Histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   0.587
SPRI_1741
Histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   0.566
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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