Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SPRI_3126Polysaccharide deacetylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (320 aa)    
Predicted Functional Partners:
SPRI_3127
Methyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.776
SPRI_6861
Secreted deacetylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.731
groS
Molecular chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
     
 0.722
SPRI_1764
Lipoprotein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.713
SPRI_3656
Xylanase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   
 0.692
groL
Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
     
 0.666
tsaD
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
       0.522
SPRI_3140
Alanine acetyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.500
SPRI_3141
Peptidase M22; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.497
SPRI_3138
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.495
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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