STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nnrDYjeF protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of [...] (495 aa)    
Predicted Functional Partners:
SPRI_5749
ADP-ribose pyrophosphatase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.959
SPRI_0831
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.952
SPRI_2676
NUDIX hydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.952
SPRI_3534
NUDIX hydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.952
SPRI_4127
DUF4031 domain-containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.952
SPRI_5220
Helicase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.935
SPRI_3144
ATP-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.920
SPRI_1260
NADH dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 
 0.904
acpS
ACP synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
       0.846
SPRI_0118
ATP-dependent RNA helicase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.838
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.