Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_3283Drug:proton antiporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (428 aa)    
Predicted Functional Partners:
SPRI_3284
Acetyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.766
SPRI_6406
Electron transfer flavoprotein subunit beta; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.619
menG
Ubiquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
     
 0.566
SPRI_0775
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
  
 0.513
SPRI_4588
RNA polymerase subunit sigma; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
  
 0.513
mqnC
Dehypoxanthine futalosine cyclase; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
       0.507
SPRI_4527
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.474
SPRI_6407
Electron transfer flavoprotein subunit alpha; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.464
SPRI_4526
DUF1025 domain-containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.455
SPRI_3282
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.442
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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