Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
rexREX family transcriptional regulator; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (241 aa)    
Predicted Functional Partners:
SPRI_3353
uroporphyrin-III C-methyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.875
hemC-2
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
       0.875
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
       0.875
SPRI_3351
Delta-aminolevulinic acid dehydratase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the ALAD family.
       0.696
SPRI_3357
Glutaredoxin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.693
SPRI_3358
Hydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.657
rpsP
30S ribosomal protein S16; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bS16 family.
   
    0.649
SPRI_4073
CarD family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
    0.578
gpmA
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
  
 0.540
SPRI_3359
RNA polymerase subunit sigma-24; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
       0.530
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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