close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_3395Lsr2-like protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (111 aa)    
Predicted Functional Partners:
SPRI_3396
N-acetylglutamate synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the acetyltransferase family.
       0.755
SPRI_3397
Transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.709
SPRI_3398
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.657
SPRI_3399
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.654
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
   
 0.609
SPRI_2739
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.593
SPRI_5103
DUF3052 domain containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.586
SPRI_6088
30S ribosomal protein S13; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
   
 0.558
SPRI_2380
vitamin-B12 independent methionine synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.556
coaX
Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
       0.555
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.