STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coaXPantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (265 aa)    
Predicted Functional Partners:
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 
 0.997
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.956
SPRI_3404
NADH-ubiquinone oxidoreductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   
 0.943
coaA
Pantothenate kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.940
SPRI_6091
DNA/pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
  
 
 0.936
SPRI_3760
Flavoprotein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.923
SPRI_3401
Nicotinate-nucleotide pyrophosphorylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family.
       0.884
SPRI_3402
Aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
       0.884
panD
Aspartate decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
  
  
 0.852
SPRI_3405
L-allo-threonine aldolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.781
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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