Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_34203-dehydroquinate dehydratase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (148 aa)    
Predicted Functional Partners:
SPRI_3419
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
       0.875
SPRI_3418
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.733
SPRI_3421
Diguanylate cyclase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
       0.724
SPRI_3422
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.724
SPRI_3423
Integral membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.674
SPRI_3417
Esterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.665
SPRI_5239
DNA primase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.638
SPRI_3365
Phosphatase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.632
SPRI_4768
Phosphatase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.599
SPRI_3412
Secreted protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.530
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.