Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
SPRI_3473LuxR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (328 aa)    
Predicted Functional Partners:
SPRI_2155
Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.893
SPRI_2558
NERD nuclease; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
    0.709
SPRI_3472
Glutamate mutase S-chain protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.641
SPRI_3474
Pyruvate carboxylase subunit A; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
       0.625
SPRI_3471
Nikkomycin biosynthsis protein SanV; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.597
SPRI_4066
Restriction endonuclease; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
    0.589
SPRI_6789
Restriction endonuclease; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
    0.589
SPRI_7005
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
    0.589
SPRI_3475
acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
       0.555
accA
Acetyl carboxylase; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
       0.555
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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