STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_3497Nikkomycin biosynthesis protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (417 aa)    
Predicted Functional Partners:
accA
Acetyl carboxylase; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
  
 
 0.943
SPRI_5054
acetyl-CoA carboxylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.943
SPRI_3475
acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
 0.917
SPRI_6117
DeoR family transcriptional regulator; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
   
   0.849
SPRI_3498
Nikkomycin biosynthesis protein SanS; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
    
0.838
SPRI_0186
PII peptide synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.824
SPRI_7167
PII peptide synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.824
SPRI_3499
Alanine dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 
 0.810
SPRI_2947
biotin--[acetyl-CoA-carboxylase] synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.764
SPRI_3500
arpA protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.747
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.