STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_3506Proteinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (513 aa)    
Predicted Functional Partners:
SPRI_3507
DNA polymerase III subunit delta; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
    0.638
SPRI_5068
DUF3145 domain-containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.573
SPRI_0186
PII peptide synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.482
SPRI_7167
PII peptide synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.482
SPRI_2687
ATP-dependent DNA helicase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
    0.464
SPRI_2080
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.454
SPRI_3320
Fructose 2,6-bisphosphatase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
   0.443
SPRI_4527
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.437
tmk
Kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
  
 0.418
SPRI_2199
Zinc metalloprotease; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.411
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.