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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_3516ATP-dependent RNA helicase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (818 aa)    
Predicted Functional Partners:
SPRI_3515
Anti-sigma B factor antagonist; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family.
       0.783
SPRI_3514
Anti-sigma regulatory factor; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.707
SPRI_3511
rRNA or tRNA methyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the methyltransferase superfamily.
       0.555
SPRI_3512
Small secreted protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.555
hppA
Potassium transporter; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.
       0.555
SPRI_2261
KH domain RNA binding protein YlqC; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the UPF0109 family.
      
 0.461
SPRI_3788
Single-stranded DNA-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
      
 0.461
SPRI_3944
RNA helicase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
      
 0.437
SPRI_4147
Cold-shock protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.433
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
      
 0.416
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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