STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_3533Colicin V biosynthesis protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (402 aa)    
Predicted Functional Partners:
SPRI_3534
NUDIX hydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
  0.821
arc
ATPase AAA; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
   
 0.790
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
   
 
 0.744
SPRI_5346
Lipoprotein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.683
SPRI_2417
Lipoprotein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.677
SPRI_2416
Lipoprotein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.667
SPRI_3536
Crp/Fnr family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.647
SPRI_2940
Lipoprotein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.644
SPRI_5082
Transpeptidase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.629
c106_07c
Acyl carrier protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.546
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.