Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
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[Homology]
Score
SPRI_3704Pyruvate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (383 aa)    
Predicted Functional Partners:
SPRI_3703
2-oxoisovalerate dehydrogenase subunit beta; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 0.999
SPRI_3702
Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.998
SPRI_3720
2-oxoisovalerate dehydrogenase subunit beta; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 0.994
SPRI_3719
Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.993
pglC
2-oxoisovalerate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 0.990
SPRI_7163
2-oxoisovalerate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 0.990
SPRI_3940
Valine dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.939
SPRI_2341
Branched-chain amino acid aminotransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.912
SPRI_6019
Class IV aminotransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.909
SPRI_5318
Dihydrolipoamide acetyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.903
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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