STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_3704Pyruvate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (383 aa)    
Predicted Functional Partners:
pglC
2-oxoisovalerate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 0.999
SPRI_3703
2-oxoisovalerate dehydrogenase subunit beta; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 0.999
SPRI_3720
2-oxoisovalerate dehydrogenase subunit beta; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 0.999
SPRI_3702
Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.998
SPRI_3719
Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.995
SPRI_7163
2-oxoisovalerate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 0.992
SPRI_3244
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 0.934
SPRI_2599
Alpha-ketoglutarate decarboxylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.921
SPRI_1688
Dihydrolipoamide dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.919
SPRI_5102
Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.919
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.