Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_3718Molybdopterin-guanine dinucleotide biosynthesis protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (299 aa)    
Predicted Functional Partners:
SPRI_3717
Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 
 0.949
SPRI_3716
Ion channel membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.849
SPRI_3715
NADPH:quinone oxidoreductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.848
SPRI_3245
2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.844
SPRI_3720
2-oxoisovalerate dehydrogenase subunit beta; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.770
SPRI_3721
3-methyl-2-oxobutanoate dehydrogenase subunit E1-alpha; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.770
fdhD
Formate dehydrogenase accessory protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
 
 
 0.758
SPRI_3244
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.731
SPRI_5531
Formate dehydrogenase oxidoreductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
   
 0.703
SPRI_3722
Transcription regulator AsnC; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.685
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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