STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_3780Putative UPF0232 protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the UPF0232 family. (186 aa)    
Predicted Functional Partners:
recF
DNA recombination protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.
  
  
 0.928
SPRI_3777
Integral membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.906
SPRI_3782
6-phosphogluconate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.885
SPRI_3783
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
   
 0.878
SPRI_4959
DNA-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   
 0.821
SPRI_4392
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.722
nucS
UPF0286 protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
  
   
 0.716
SPRI_4595
DUF3039 domain-containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.705
SPRI_6179
Transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.705
SPRI_2042
dUTPase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.702
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.