Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (220 aa)    
Predicted Functional Partners:
SPRI_2968
Uridine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.989
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.969
pyrF-2
Orotidine 5'-phosphate decarboxylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 
 0.960
SPRI_2983
Pyrimidine-nucleoside phosphorylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.955
pyrF
Putative integron gene cassette protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.932
SPRI_3313
Cytosine deaminase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.925
SPRI_3219
Hydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.924
pyrR
Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
 0.921
SPRI_4006
5'-nucleotidase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the 5'-nucleotidase family.
     
 0.912
psuG
Pigment biosynthetic protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.
    
  0.908
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.