Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
SPRI_3933ArsR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (171 aa)    
Predicted Functional Partners:
SPRI_3935
Mycothiol maleylpyruvate isomerase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.814
purS
Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...]
       0.764
purQ
Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...]
       0.764
purL
Phosphoribosylglycinamide synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the tr [...]
       0.764
SPRI_3934
Peptidase M23; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.762
SPRI_3936
Lipoprotein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.711
SPRI_3929
Putative Lsr2-like protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.655
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
       0.637
purM
Phosphoribosylaminoimidazole synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.551
SPRI_6874
Protein of unknown function DUF574; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.469
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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