Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_3970Signal transduction histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (524 aa)    
Predicted Functional Partners:
SPRI_3515
Anti-sigma B factor antagonist; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family.
 
   0.832
SPRI_6891
Metal ABC transporter substrate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family.
 
   0.766
SPRI_0646
Integral membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.757
SPRI_0527
Stage II sporulation protein E; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.734
SPRI_3969
NADH dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.716
SPRI_4488
Metal ABC transporter substrate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family.
 
   0.690
SPRI_4242
Anti-sigma factor antagonist; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family.
 
   0.652
SPRI_3968
TetR-family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.632
SPRI_7008
Phosphatase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.595
SPRI_4097
Diguanylate cyclase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.594
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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