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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_4060Integrase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family. (419 aa)    
Predicted Functional Partners:
SPRI_4061
DNA-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.822
SPRI_4062
Replication initiation protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.819
SPRI_2658
PF02586 family protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the SOS response-associated peptidase family.
   
  
 0.465
SPRI_4546
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.459
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.457
whiA
Sporulation protein; Involved in cell division and chromosome segregation.
   
    0.453
SPRI_4337
Integrase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.409
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.