STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_4093Metallopeptidase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (467 aa)    
Predicted Functional Partners:
SPRI_4092
Secreted protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.746
SPRI_4088
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.643
SPRI_3253
Leupeptin-inactivating enzyme 1; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 
 0.484
SPRI_1175
Proteinase inhibitor I4 serpin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.474
SPRI_3917
Amidohydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 
 0.444
xseB
Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
     
 0.421
SPRI_4069
PhoU family transcriptional regulator; Plays a role in the regulation of phosphate uptake.
  
  
 0.412
fusA
Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
   
 
 0.401
fusA-2
Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
   
 
 0.401
SPRI_3537
SPFH/Band 7/PHB domain protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 
 0.401
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.