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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_4099Sugar kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. (311 aa)    
Predicted Functional Partners:
SPRI_6864
PTS lactose transporter subunit IIC; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.996
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
  
  
 0.924
pfkA-2
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
  
  
 0.923
pfp
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
     
 0.913
SPRI_0508
Tagatose-bisphosphate aldolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.878
SPRI_0510
Alkaline phosphatase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.847
SPRI_6862
D-beta-D-heptose 1-phosphate adenosyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.843
SPRI_0796
Transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.820
SPRI_4885
Ribose 5-phosphate isomerase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.807
SPRI_2957
DeoR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.805
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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