Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_4108Threonine synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (435 aa)    
Predicted Functional Partners:
thrB
Serine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
 
 0.985
SPRI_2926
Threonine dehydratase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
0.942
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
   
 0.941
SPRI_4109
Molybdenum cofactor biosynthesis protein MoaD; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.938
SPRI_2786
Threonine synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 
0.923
SPRI_2535
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
  
 
0.922
SPRI_6400
Threonine aldolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.919
tdh
L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.
   
 
 0.902
SPRI_2536
Homoserine dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.872
SPRI_4638
Molybdenum cofactor biosynthesis protein MoaD; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.742
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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