Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_4137Helicase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (573 aa)    
Predicted Functional Partners:
SPRI_4139
DNA-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.854
SPRI_2103
ATP-dependent helicase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.776
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.726
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.711
SPRI_4138
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.645
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 0.644
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.623
SPRI_5932
DNA polymerase I; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 0.582
SPRI_3089
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
  0.508
SPRI_4140
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.496
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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