close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_4145Hydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (214 aa)    
Predicted Functional Partners:
SPRI_4625
FAD-linked oxidase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 0.906
SPRI_4037
HAD hydrolase, family IA; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
  0.900
SPRI_4141
Iron-siderophore ABC transporter substrate-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.625
SPRI_4142
ABC transporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.602
SPRI_4144
Iron ABC transporter permease; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
  
    0.590
SPRI_4143
Iron ABC transporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
       0.584
SPRI_4139
DNA-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.555
SPRI_4140
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.555
moaA
Molybdenum cofactor biosynthesis protein MoeA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
    0.490
SPRI_5556
Uridine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.452
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.