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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_4191TetR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (202 aa)    
Predicted Functional Partners:
SPRI_4190
Lipase_GDSL_2 domain containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.709
SPRI_4192
Methyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
   0.662
SPRI_1476
MarR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.598
SPRI_4189
Methyltransferase type 11; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
   0.588
SPRI_2796
Tat pathway signal sequence domain protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.583
SPRI_5959
Transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.565
SPRI_4228
Transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.557
SPRI_5308
Regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.505
SPRI_4193
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.475
SPRI_0562
Transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
   
 0.469
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.