STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (402 aa)    
Predicted Functional Partners:
SPRI_2355
3-phosphoglycerate dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 0.991
SPRI_5717
Phosphoserine phosphatase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.976
SPRI_2535
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
   
 0.938
SPRI_2786
Threonine synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.938
SPRI_3829
Hydrolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.938
SPRI_4108
Threonine synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.938
SPRI_6448
Cysteine synthase/cystathionine beta-synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.918
SPRI_4201
Putative ATP/GTP-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.878
SPRI_0500
2-hydroxyacid dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 
 0.819
SPRI_2360
Dihydrofolate reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 
 0.811
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.