close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_4243Calcium-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (171 aa)    
Predicted Functional Partners:
SPRI_1844
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.936
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
 0.915
SPRI_1192
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 0.898
SPRI_5916
Peptidylprolyl isomerase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.867
SPRI_5917
Peptidyl-prolyl cis-trans isomerase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
   
 0.867
SPRI_3007
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.851
SPRI_1482
Putative protein piccolo; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.765
SPRI_6759
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.762
SPRI_4242
Anti-sigma factor antagonist; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family.
       0.740
SPRI_5265
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.727
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.