Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_4249Cyclase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (308 aa)    
Predicted Functional Partners:
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
  
  
 0.900
SPRI_4250
Short-chain dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.838
SPRI_6514
Cupin 2; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
    0.833
SPRI_0803
Transposase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.817
SPRI_4251
acyl-CoA dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
    0.808
SPRI_6558
Extradiol ring-cleavage dioxygenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.639
SPRI_1507
FAD-dependent oxidoreductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.603
SPRI_4252
Molecular chaperone GroES; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.601
SPRI_0148
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.441
kynA
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
  
  
 0.441
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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