Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_4263Oxidase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (226 aa)    
Predicted Functional Partners:
pdxS
Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
  
 
 0.926
pdxH
Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
  
  
 
0.919
pdxT
Glutamine amidotransferase subunit pdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
    
 0.918
SPRI_4043
Aldo/keto reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.901
SPRI_6531
Oxidoreductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.901
SPRI_4264
acetyl-CoA acetyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.825
SPRI_6613
Pyridoxamine 5'-phosphate oxidase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.546
SPRI_4270
TetR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.530
SPRI_4265
acyl-CoA dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.522
SPRI_4260
Monooxygenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.496
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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