Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_4288F420-dependent oxidoreductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (306 aa)    
Predicted Functional Partners:
SPRI_4289
Dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.769
SPRI_4290
Luciferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
    
0.654
SPRI_6783
5,10-methylene tetrahydromethanopterin reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.603
fbiA
2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
 
   
 0.590
snaA
Pristinamycin IIA synthase subunit A; Catalyzes the oxidation of the proline residue of pristinamycin IIB (PIIB) to pristinamycin IIA (PIIA).
  
  
 0.553
SPRI_7168
Pristinamycin IIA synthase subunit A; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.553
SPRI_4287
Thioesterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.549
fbiB
F420-0--gamma-glutamyl ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0.
 
  
 0.484
SPRI_4291
Aminoacylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.466
snaB
Alkanesulfonate monooxygenase; Catalyzes the oxidation of the proline residue of pristinamycin IIB (PIIB) to pristinamycin IIA (PIIA).
  
  
 0.457
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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