Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_4299F420-dependent oxidoreductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (275 aa)    
Predicted Functional Partners:
SPRI_4297
Phosphoesterase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.679
SPRI_4317
FO synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.675
SPRI_6162
benzoylsuccinyl-CoA thiolase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.557
SPRI_4290
Luciferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.525
SPRI_5882
F420-dependent oxidoreductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.503
fbiA
2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
 
   
 0.499
fbiB
F420-0--gamma-glutamyl ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0.
 
  
 0.477
SPRI_4298
Transposase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.443
SPRI_5497
CoA-transferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
     0.433
SPRI_0186
PII peptide synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.425
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.