STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_4319Sodium-coupled permease; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (527 aa)    
Predicted Functional Partners:
SPRI_2349
Proline dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.782
SPRI_4326
Membrane protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.745
SPRI_2155
Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.739
SPRI_4320
Short-chain dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.721
SPRI_4322
Toxin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.715
SPRI_4321
Hypothetical protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.676
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
  
 0.551
SPRI_4325
D-alanyl-D-alanine carboxypeptidase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family.
     
 0.505
SPRI_4324
GPP34 domain-containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.479
pxpA
Lactam utilization protein LamB; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
  
    0.476
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.