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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_4344MarR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (171 aa)    
Predicted Functional Partners:
SPRI_4345
Extradiol ring-cleavage dioxygenase III subunit B; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.855
mca
GlcNAc-PI de-N-acetylase; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
  
     0.576
clpS
ATP-dependent Clp protease adapter protein clpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
 
  
 0.557
SPRI_1671
DsbA oxidoreductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.555
SPRI_2479
MarR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   
 0.504
SPRI_4880
DSBA oxidoreductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.494
mshD
Mycothiol acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
  
     0.478
SPRI_2329
Polyisoprenoid-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the UPF0312 family.
 
   
 0.457
SPRI_2816
Malonic semialdehyde reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.416
mshB
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
  
     0.415
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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