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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_4345Extradiol ring-cleavage dioxygenase III subunit B; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (265 aa)    
Predicted Functional Partners:
SPRI_4344
MarR family transcriptional regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.855
SPRI_4341
M6 family metalloprotease; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.692
SPRI_0720
Pirin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the pirin family.
 
  
 0.602
SPRI_6309
Pirin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the pirin family.
 
  
 0.594
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.568
SPRI_3690
Pirin; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the pirin family.
 
  
 0.556
SPRI_6117
DeoR family transcriptional regulator; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.451
SPRI_5074
Pirin domain-containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the pirin family.
 
  
 0.423
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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