glmU protein (Streptomyces pristinaespiralis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

glmU

N-acetylglucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (540 aa)

Predicted Functional Partners:

glmM

0.986

prs

0.975

murA

0.960

SPRI_3113

0.933

SPRI_1822

0.926

SPRI_4360

0.922

SPRI_2466

0.921

SPRI_6172

0.896

SPRI_0994

0.863

SPRI_4405

0.863

Your Current Organism:

Streptomyces pristinaespiralis

NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SPRI_0994	SPRI_4360	SPRI_0994	SPRI_4360	UDP-glucose 4-epimerase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	UTP--glucose-1-phosphate uridylyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.943
SPRI_0994	SPRI_4405	SPRI_0994	SPRI_4405	UDP-glucose 4-epimerase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	UDP-glucose 4-epimerase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	0.910
SPRI_0994	SPRI_6172	SPRI_0994	SPRI_6172	UDP-glucose 4-epimerase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Mannose-1-phosphate guanyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.882
SPRI_0994	glmU	SPRI_0994	SPRI_4420	UDP-glucose 4-epimerase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	N-acetylglucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	0.863
SPRI_1822	SPRI_4360	SPRI_1822	SPRI_4360	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	UTP--glucose-1-phosphate uridylyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.854
SPRI_1822	SPRI_6172	SPRI_1822	SPRI_6172	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Mannose-1-phosphate guanyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.873
SPRI_1822	glmU	SPRI_1822	SPRI_4420	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	N-acetylglucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	0.926
SPRI_1822	murA	SPRI_1822	SPRI_4593	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.900
SPRI_2466	glmU	SPRI_2466	SPRI_4420	Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.	N-acetylglucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	0.921
SPRI_2466	prs	SPRI_2466	SPRI_4419	Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.	Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.	0.534
SPRI_3113	glmU	SPRI_3113	SPRI_4420	UDP-glucose/GDP-mannose dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.	N-acetylglucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	0.933
SPRI_4360	SPRI_0994	SPRI_4360	SPRI_0994	UTP--glucose-1-phosphate uridylyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	UDP-glucose 4-epimerase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.943
SPRI_4360	SPRI_1822	SPRI_4360	SPRI_1822	UTP--glucose-1-phosphate uridylyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.854
SPRI_4360	SPRI_4405	SPRI_4360	SPRI_4405	UTP--glucose-1-phosphate uridylyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	UDP-glucose 4-epimerase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	0.948
SPRI_4360	SPRI_6172	SPRI_4360	SPRI_6172	UTP--glucose-1-phosphate uridylyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Mannose-1-phosphate guanyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.894
SPRI_4360	glmM	SPRI_4360	SPRI_3156	UTP--glucose-1-phosphate uridylyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.	0.447
SPRI_4360	glmU	SPRI_4360	SPRI_4420	UTP--glucose-1-phosphate uridylyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	N-acetylglucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	0.922
SPRI_4360	murA	SPRI_4360	SPRI_4593	UTP--glucose-1-phosphate uridylyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.848
SPRI_4360	prs	SPRI_4360	SPRI_4419	UTP--glucose-1-phosphate uridylyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.	0.475
SPRI_4405	SPRI_0994	SPRI_4405	SPRI_0994	UDP-glucose 4-epimerase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family.	UDP-glucose 4-epimerase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.910

page 1 of 3

Server load: low (26%) [HD]

Permalink

Network

Neighborhood

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About