SPRI_4467 protein (Streptomyces pristinaespiralis)

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Score

SPRI_4467

Cystathionine beta-synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (461 aa)

Predicted Functional Partners:

SPRI_2931

0.996

SPRI_3832

0.995

SPRI_5717

0.945

SPRI_2926

0.941

SPRI_0180

0.939

SPRI_5899

0.939

glyA

0.933

glyA-2

0.933

glyA-3

0.933

ahcY

0.929

Your Current Organism:

Streptomyces pristinaespiralis

NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SPRI_0180	SPRI_2926	SPRI_0180	SPRI_2926	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Threonine dehydratase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.891
SPRI_0180	SPRI_2931	SPRI_0180	SPRI_2931	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Cystathionine gamma-synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.966
SPRI_0180	SPRI_3832	SPRI_0180	SPRI_3832	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Cystathionine gamma-lyase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.966
SPRI_0180	SPRI_4467	SPRI_0180	SPRI_4467	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Cystathionine beta-synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.939
SPRI_0180	SPRI_5899	SPRI_0180	SPRI_5899	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.980
SPRI_0180	ahcY	SPRI_0180	SPRI_0178	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.	0.989
SPRI_0180	glyA	SPRI_0180	SPRI_2404	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.931
SPRI_0180	glyA-2	SPRI_0180	SPRI_2526	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.931
SPRI_0180	glyA-3	SPRI_0180	SPRI_3049	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.931
SPRI_2926	SPRI_0180	SPRI_2926	SPRI_0180	Threonine dehydratase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.891
SPRI_2926	SPRI_2931	SPRI_2926	SPRI_2931	Threonine dehydratase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Cystathionine gamma-synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.901
SPRI_2926	SPRI_3832	SPRI_2926	SPRI_3832	Threonine dehydratase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Cystathionine gamma-lyase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.910
SPRI_2926	SPRI_4467	SPRI_2926	SPRI_4467	Threonine dehydratase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Cystathionine beta-synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.941
SPRI_2926	SPRI_5717	SPRI_2926	SPRI_5717	Threonine dehydratase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Phosphoserine phosphatase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	0.920
SPRI_2926	SPRI_5899	SPRI_2926	SPRI_5899	Threonine dehydratase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.891
SPRI_2926	ahcY	SPRI_2926	SPRI_0178	Threonine dehydratase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.	0.829
SPRI_2926	glyA	SPRI_2926	SPRI_2404	Threonine dehydratase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.936
SPRI_2926	glyA-2	SPRI_2926	SPRI_2526	Threonine dehydratase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.936
SPRI_2926	glyA-3	SPRI_2926	SPRI_3049	Threonine dehydratase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.936
SPRI_2931	SPRI_0180	SPRI_2931	SPRI_0180	Cystathionine gamma-synthase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.966