Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_4518GDP-mannose pyrophosphorylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (363 aa)    
Predicted Functional Partners:
SPRI_2962
Phosphomannomutase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.964
SPRI_4528
Phosphomannomutase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.953
SPRI_2000
GDP-mannose dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
  
 
 0.948
SPRI_6172
Mannose-1-phosphate guanyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
0.942
cpp24
Glucose-1-phosphate thymidylyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
0.896
SPRI_4930
Glucose-1-phosphate thymidylyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
0.895
SPRI_3362
NAD-dependent dehydratase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.878
SPRI_4519
3-methyladenine DNA glycosylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
    0.873
SPRI_4506
UDP-glucose 6-dehydrogenase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.870
glmU
N-acetylglucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
   
0.838
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
Server load: low (20%) [HD]