Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_4531Mannose-6-phosphate isomerase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (392 aa)    
Predicted Functional Partners:
SPRI_4528
Phosphomannomutase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.983
SPRI_6864
PTS lactose transporter subunit IIC; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
  
 0.952
SPRI_6172
Mannose-1-phosphate guanyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 0.947
pgi
Glucose-6-phosphate isomerase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the GPI family.
 
 
 0.941
SPRI_2638
Glucosamine-6-phosphate deaminase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
    
 0.922
glmS
Glutamine amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.922
glmS-2
Glutamine amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.922
SPRI_2962
Phosphomannomutase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.920
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
    
 0.913
pfp
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
    
 0.913
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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