Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
SPRI_4543Two-component system response regulator; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (225 aa)    
Predicted Functional Partners:
SPRI_4544
Histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.997
SPRI_2971
Histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.980
SPRI_5086
Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 0.980
SPRI_2155
Two-component system sensor kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.961
lpqB
Lipoprotein LpqB; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
     
 0.882
mtnA
Initiation factor 2B subunit alpha; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
       0.853
SPRI_4070
Histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.821
SPRI_2043
Histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.815
SPRI_1325
Histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
   0.800
SPRI_2491
Histidine kinase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
 
 0.795
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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