STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRI_4584uroporphyrinogen-III synthetase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (381 aa)    
Predicted Functional Partners:
SPRI_6011
Uroporphyrinogen III methylase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family.
 
 
 0.989
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.983
hemC-2
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.983
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.972
SPRI_4583
MFS transporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.957
SPRI_3353
uroporphyrin-III C-methyltransferase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
 
 0.952
SPRI_3351
Delta-aminolevulinic acid dehydratase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the ALAD family.
  
 
 0.867
SPRI_5022
Nitrite reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.823
SPRI_5021
Nitrite reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.736
SPRI_5023
Nitrite reductase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
 
  
 0.704
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.