Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPRI_4589Helicase; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology. (788 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.736
rpoC
Nos4; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.733
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
   0.719
SPRI_4587
RNA polymerase sigma factor SigL; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
       0.713
SPRI_4588
RNA polymerase subunit sigma; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.713
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
   0.688
SPRI_4586
DUF1470 domain-containing protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.659
rbpA-2
Membrane protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
  
 
   0.582
SPRI_2707
ATP-binding protein; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
  
     0.552
SPRI_4583
MFS transporter; Derived by Prodigal V2.6.2 analysis using gene prediction method: Protein Homology.
       0.530
Your Current Organism:
Streptomyces pristinaespiralis
NCBI taxonomy Id: 38300
Other names: S. pristinaespiralis
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